Comparisons of patient and technique survival were made for 143 CAPD and 293 HD patients between January 1989 and December 1993. For the statistical analysis, we used the PC-SAS V6.04. For the univariate analysis, we applied the Life-table
survival
analysis, using the Logrank test. For the multivariate analysis, the Cox's proportional hazards regression model was used. There were five risk factors; sex, age, cardiovascular disease, diabetes mellitus and smoking.
Withot adjustments for the risk factors, patients 5-year survival as higher in HD than CAPD, 85.4% versus 49.7%, respectively(p=0.0001). Technique 5-year survival was better in HD than in CAPD, 86.3% versus 74.7% respectively(p=0.0238).
Cardiovascular disease, old age(more than 60) and smoking were associated with a shorter patient-survival on treatment. With the application of the Cox's model, there is a fivefold risk increase with cardiovascular disease. twofold with old age
and
twofold with smoking. CAPD would be a good alternative to HD for the high risk patients with cardiovascular disease (relative risk in HD and CAPD, 6.64 versus 4.38, respectively) and old age (relative risk in HD and CAPD, 2.97 versus 1.50,
respectively).
With the application of the Cox's model in technique survival, there is a twofold increased risk with the diabetes mellitus. Of the risk factors, old age and diabetes mellitus were found to be significantly associated with HD-technique survival.
CAPD
would be a good alternative to HD for high risk patients with old age(relative risk in HD and CAPD, 2.82 versus 0.74, respectively) and diabetes mellitus (relative risk in HAD and CAPD, 2.82 versus 0.74, respectively) and diabetes
mellitus(relative
risk
in HD and CAPD, 3.47 versus 1.74, respectively).
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